A Bayesian method for jointly estimating allele age and selection intensity
نویسندگان
چکیده
منابع مشابه
A Bayesian method for jointly estimating allele age and selection intensity.
The problem of jointly estimating the intensity of past selection affecting an allele and the allele's age is formulated in a Bayesian framework. The prior distribution of allele age given its frequency is obtained from existing population genetics theory. The prior distribution of selection intensity is assumed to reflect the fact that positive selection on a new mutant is more likely to be we...
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ژورنال
عنوان ژورنال: Genetics Research
سال: 2008
ISSN: 0016-6723,1469-5073
DOI: 10.1017/s0016672307008944